You should be able to secure your Cloudflare account if you believe it's been compromised?
The way that DNS proxies work is they sit in the middle of requests to you, so requests are redirected, hiding your IPs and theoretically securing your connection somewhat. Blocking port 443 will just prevent traffic, but you should instead focus on securing your accounts and tackling the original problem.
What is your platform, what servers are running, how are you sure that the Cloudflare DNS proxy is the culprit?
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