The "normal" level seems to cope with fast connections just fine, I am on 500 Mbps fiber connection and that's what I use.
I would set it to "experimental" only with 1 Gigabit connections, and it would have to be tested to make sure everything works. In some OSes (Windows 7 for sure, hasn't been tested much with later Windows 10 iterations),"Experimental" caused issues with accessing network shares, Crashplan backups, Outlook accessing mail servers.
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