The TCP Optimizer best settings depend on the download/upload speed of your connection. You can always revert to the Windows defaults as well.
There are no specific different settings that would be required for LTE. I would suggest starting with the default settings, making small changes, then rebooting and testing. You can read what each setting does in the documentation here: https://www.speedguide.net/articles/...8-10-2012-5821
I hope this helps, let us know what works well for your connection, and what speeds you are able to get.
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