With all the talk about these new NVMe M.2 drives I was starting to wonder what a current drive configuration should look like? Is it still prudent to run your OS and programs off of one drive and then keep data on another? Right now between my 2 drives I'm only using about 210 Gb of space and I don't see myself adding another 100 Gb of photos anytime soon. Would it make sense just to buy and use only one NVMe 500 Gb drive?

My next question is what does your drive configuration look like?